Sodium Hydroxide → HCID 22494620、化合物
反応式
C([N:4]1[CH2:9][CH2:8][N:7]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][O:23][CH3:24])=[CH:12][CH:11]=2)[CH2:6][CH2:5]1)(=O)C.[OH-].[Na+]>Cl>[CH3:24][O:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][O:16][C:13]1[CH:14]=[CH:15][C:10]([N:7]2[CH2:8][CH2:9][NH:4][CH2:5][CH2:6]2)=[CH:11][CH:12]=1参加物
4
反応条件
- 温度
- 75 °C
実験手順
A mixture of 1-acetyl-4-[4-(6-methoxyhexyloxy)phenyl]piperazine (4.87 g) and 6N-hydrochloric acid (50 ml) was heated at 75° C. for 3 hours. After cooling, the solution was adjusted to pH 11 with 25% sodium hydroxide aqueous solution then the resulting precipitate was collected by filtration, washed with water and dried under reduced pressure to give 4-[4-(6-methoxyhexyloxy)phenyl]piperazine (3.77 g) as a pale brown solid.