化工社化工社 化学情報印刷レポート · 研究参考用
Piperidine → (E,E)-2-(Benzylaminocarbonyl)-3-(4-hydroxy-3-methoxystyryl)acrylonitrile
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Piperidine | HCID 8082 | — |
| 反応物 | 2-Propenal, 3-(4-hydroxy-3-methoxyphenyl)- | HCID 9984 | — |
| 反応物 | N-(cyanoacetyl)benzylamide | HCID 178511179 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | (E,E)-2-(Benzylaminocarbonyl)-3-(4-hydroxy-3-methoxystyryl)acrylonitrile | HCID 11522842 | — |
反応手順
The compound was prepared as described in Example 37 by adding piperidine to a solution of 4-hydroxy-3-methoxycinnamaldehyde (35 mg, 0.2 mmol) and N-(cyanoacetyl)benzylamide (34 mg, 0.2 mmol) in ethanol. After recrystallization from ethanol-water a yellow solid was obtained (50 mg, 75%). The product gave the following analytical data:
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07598419B2 |
| 出典データセット | uspto-grants-2009_10 |
| ORD ID | ord-1076ebe740ce40c7a1d72d72c5535048 |
| 出典メモ | uspto-grants-2009_10 |