Piperidine → HCID 11500983、化合物

HRID 1818047

反応式

HRID 1818047 の反応式
N1CCCCC1.[OH:7][C:8]1[CH:9]=[C:10]([CH:15]=[CH:16][C:17]=1[OH:18])[CH:11]=[CH:12][CH:13]=O.[C:19]([CH2:21][C:22]([NH:24][CH2:25][C:26]1[CH:31]=[CH:30][CH:29]=[C:28]([F:32])[CH:27]=1)=[O:23])#[N:20]>C(O)C>[F:32][C:28]1[CH:27]=[C:26]([CH:31]=[CH:30][CH:29]=1)[CH2:25][NH:24][C:22](/[C:21](=[CH:13]/[CH:12]=[CH:11]/[C:10]1[CH:15]=[CH:16][C:17]([OH:18])=[C:8]([OH:7])[CH:9]=1)/[C:19]#[N:20])=[O:23]

参加物

5

反応物 3

HCID 8082PiperidineHCID 4430343-(3,4-Dihydroxy-phenyl)-2-propenalHCID 289708802-cyano-N-[(3-fluorophenyl)methyl]acetamide

生成物 1

HCID 11500983HCID 11500983、化合物

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒

実験手順

The compound was prepared as described in Example 37 by adding piperidine to a solution of 3,4-dihydroxycinnamaldehyde (35 mg, 0.2 mmol) and 2-cyano-N-(3-fluorobenzyl)acetamide (38 mg, 0.2 mmol) in ethanol. After recrystallization from ethanol-water a yellow solid was obtained (51 mg, 75%). The product gave the following analytical data:

後処理

  1. customThe compound was prepared
  2. customAfter recrystallization from ethanol-water a yellow solid
  3. customwas obtained (51 mg, 75%)
  4. customThe product gave the following analytical data

出典と根拠

ORDレコード
ord-8b4890e42bc4430b84d5f68d83900e42
出典データセット
uspto-grants-2009_10
特許番号
US07598419B2

関連ノート

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