Sodium Carbonate → 7-Bromo-4-[1-(2,5-difluorophenyl)methylidene]-1,2,3,4-tetrahydro-[1,8]naphthyridine

反応式

C([O-])([O-])=O.[Na+].[Na+].[Br:7][C:8]1[N:17]=[C:16]2[C:11]([C:12](=[CH:18]I)[CH2:13][CH2:14][NH:15]2)=[CH:10][CH:9]=1.[F:20][C:21]1[CH:26]=[CH:25][C:24]([F:27])=[CH:23][C:22]=1B(O)O.C(OCC)(=O)C.CCCCCC>C1(C)C=CC=CC=1.C(O)C.C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1>[Br:7][C:8]1[N:17]=[C:16]2[C:11]([C:12](=[CH:18][C:25]3[CH:26]=[C:21]([F:20])[CH:22]=[CH:23][C:24]=3[F:27])[CH2:13][CH2:14][NH:15]2)=[CH:10][CH:9]=1