HCID 14801183、化合物 → 3-(Methoxymethyl)-2-methylaniline
反応式
[CH3:1][C:2]1[C:10]([N+:11]([O-])=O)=[CH:9][CH:8]=[CH:7][C:3]=1[CH2:4][O:5][CH3:6]>CCOC(C)=O.CCO.[Pd]>[CH3:6][O:5][CH2:4][C:3]1[C:2]([CH3:1])=[C:10]([CH:9]=[CH:8][CH:7]=1)[NH2:11]参加物
4
実験手順
A mixture of methyl 2-methyl-3-nitrobenzyl ether (0.19 g, 1.05 mmol), and 5% Pd/C (70 mg) in EtOAc/EtOH 1:1 (14 ml) was hydrogenated at 1 atm over night. The mixture was filtered through Celite, and the filtrate was concentrated to give the title compound 125 mg (78%) as a yellow oil.
後処理
- waitwas hydrogenated at 1 atm over night
- filtrationThe mixture was filtered through Celite
- concentrationthe filtrate was concentrated
出典と根拠
- ORDレコード
- ord-0a1c6ec283e84342b376c613275e3f38
- 出典データセット
- uspto-grants-2006_05
- 特許番号
- US07037925B2
反応ノート
読み込み中…