Piperidine → 4-Piperidinylbut-1-ene

HRID 1824513

反応式

HRID 1824513 の反応式
Br[CH2:2][CH2:3][CH:4]=[CH2:5].[NH:6]1[CH2:11][CH2:10][CH2:9][CH2:8][CH2:7]1>>[N:6]1([CH2:7][CH2:8][CH:9]=[CH2:10])[CH2:11][CH2:5][CH2:4][CH2:3][CH2:2]1

参加物

3

反応物 2

HCID 8082PiperidineHCID 21241Homoallyl bromide

生成物 1

HCID 45622824-Piperidinylbut-1-ene収率 93.4%

実験手順

4-Bromobut-1-ene (1.35 g) was treated with piperidine (1.7 g) and heated at reflux for 3 hours. The mixture was cooled to ambient temperature, filtered and the residue washed with ether (50 mL). The combined filtrate and washings were evaporated to give the title compound (1.3 g).

後処理

  1. temperatureheated
  2. temperatureat reflux for 3 hours
  3. filtrationfiltered
  4. washthe residue washed with ether (50 mL)
  5. customThe combined filtrate and washings were evaporated

出典と根拠

ORDレコード
ord-adb29397f4884d54a3b13354f001a0f2
出典データセット
uspto-grants-2006_05
特許番号
US07041827B2

関連ノート

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