3-Methoxy-4-methyl-2-nitropyridine → 2-Pyridinamine,3-methoxy-4-methyl-(9CI)

HRID 1828529ノート

反応式

HRID 1828529 の反応式
[CH3:1][O:2][C:3]1[C:4]([N+:10]([O-])=O)=[N:5][CH:6]=[CH:7][C:8]=1[CH3:9]>CO.[Pd]>[NH2:10][C:4]1[C:3]([O:2][CH3:1])=[C:8]([CH3:9])[CH:7]=[CH:6][N:5]=1

参加物

4

反応物 1

HCID 149295773-Methoxy-4-methyl-2-nitropyridine2 回

生成物 1

HCID 220637652-Pyridinamine,3-methoxy-4-methyl-(9CI)収率 103.4%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

The 3-methoxy-4-methyl-2-nitropyridine (1 g) obtained in (A) was dissolved in methanol (50 ml), added with 5% Pd/C (200 mg), and stirred at a pressure of 40 psi for 2 hours under hydrogen atmosphere. After the catalyst was removed by filtration, the solvent was evaporated under reduced pressure to obtain the title compound (850 mg) as yellow oil.

後処理

  1. customAfter the catalyst was removed by filtration
  2. customthe solvent was evaporated under reduced pressure

出典と根拠

ORDレコード
ord-51b8d38c280b4a1b873c80a8120d7d35
出典データセット
uspto-grants-2006_06
特許番号
US07056917B2

反応ノート

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