Hydrochloric Acid → 3-Cyclobutoxy-phenol
反応式
[CH:1]1([O:5][C:6]2[CH:7]=[C:8]([O:12]C(=O)C)[CH:9]=[CH:10][CH:11]=2)[CH2:4][CH2:3][CH2:2]1.[OH-].[Na+].Cl>CO>[CH:1]1([O:5][C:6]2[CH:7]=[C:8]([OH:12])[CH:9]=[CH:10][CH:11]=2)[CH2:4][CH2:3][CH2:2]1参加物
5
実験手順
Acetic acid 3-cyclobutoxy-phenyl ester (340 mg, 1.65 mmol) was dissolved in methanol (6 ml) and 1 M sodium hydroxide solution (2 ml, 2 mmol) was added. The reaction mixture was stirred at room temperature for 24 hours and then was acidified with 2 M hydrochloric acid. The reaction mixture was extracted with ethyl acetate and the organic solution was dried over magnesium sulphate and concentrated in-vacuo to give 3-cyclobutoxy-phenol (300 mg).
後処理
- extractionThe reaction mixture was extracted with ethyl acetate
- dry with materialthe organic solution was dried over magnesium sulphate
- concentrationconcentrated in-vacuo
出典と根拠
- ORDレコード
- ord-a1412062583f43528e852cbfcd2ae396
- 出典データセット
- uspto-grants-2006_06
- 特許番号
- US07060717B2
反応ノート
読み込み中…