Diethylamine → HCID 22059719、化合物

HRID 1828899ノート

反応式

HRID 1828899 の反応式
[CH2:1]([NH:3][CH2:4][CH3:5])[CH3:2].Cl[CH2:7][C:8]([C:10]1[C:11]([CH3:18])=[C:12]([CH:16]=[O:17])[NH:13][C:14]=1[CH3:15])=[O:9]>C1COCC1>[CH3:18][C:11]1[C:10]([C:8](=[O:9])[CH2:7][N:3]([CH2:4][CH3:5])[CH2:1][CH3:2])=[C:14]([CH3:15])[NH:13][C:12]=1[CH:16]=[O:17]

参加物

4

反応物 2

HCID 8021DiethylamineHCID 220598554-(2-chloroacetyl)-3,5-dimethyl-1H-pyrrole-2-carbaldehyde

生成物 1

HCID 22059719HCID 22059719、化合物

試薬・触媒・溶媒 1

HCID 8028Tetrahydrofuran溶媒

実験手順

Diethylamine (5 ml) was added to a solution of 4-(2-Chloroacetyl)-3,5-dimethylpyrrole-2-carboxaldehyde (1 g, 5 mmol) in THF (20 ml). The mixture was stirred at room temperature for 24 h. The solvent was removed under reduced pressure and the residue was treated with water, NaHCO3 (5%) and extracted with dichloromethane. After drying and filtering, the solvent was removed and the residue was used without further purification.

後処理

  1. customThe solvent was removed under reduced pressure
  2. additionthe residue was treated with water, NaHCO3 (5%)
  3. extractionextracted with dichloromethane
  4. customAfter drying
  5. filtrationfiltering
  6. customthe solvent was removed
  7. customthe residue was used without further purification

出典と根拠

ORDレコード
ord-f5763b2445974eb093d9337134f23510
出典データセット
uspto-grants-2006_06
特許番号
US07060822B1

反応ノート

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