Carbamic chloride, N-methyl-N-phenyl- → Methyl-phenyl-carbamic Acid 4-hydroxymethyl-pyrazol-1-yl Ester

HRID 1831289

反応式

HRID 1831289 の反応式
[OH:1][N:2]1[CH:6]=[C:5]([CH2:7][OH:8])[CH:4]=[N:3]1.[CH3:9][N:10]([C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[C:11](Cl)=[O:12]>>[OH:8][CH2:7][C:5]1[CH:4]=[N:3][N:2]([O:1][C:11](=[O:12])[N:10]([CH3:9])[C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:6]=1

参加物

3

反応物 2

HCID 77969Carbamic chloride, N-methyl-N-phenyl-HCID 220476851-Hydroxy-4-hydroxymethylpyrazole

生成物 1

HCID 69517970Methyl-phenyl-carbamic Acid 4-hydroxymethyl-pyrazol-1-yl Ester

実験手順

The title compound was prepared from 1-hydroxy-4-hydroxymethylpyrazole and N-methyl-N-phenylcarbamoyl chloride applying the general procedure 8. The crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (62%, oil).

後処理

  1. customThe crude product was purified by flash chromatography (Quad flash 12, EtOAc-heptane) (62%, oil)

出典と根拠

ORDレコード
ord-b88859a656dc439996cc7e400ae7589d
出典データセット
uspto-grants-2006_06
特許番号
US07067517B2

関連ノート

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