2-Butanamine, 1-methoxy- → [4-(2,4-Dichloro-phenyl)-3-nitro-pyridin-2-yl]-(1-methoxymethyl-propyl)-amine

HRID 1831510

反応式

HRID 1831510 の反応式
Cl[C:2]1[C:7]([N+:8]([O-:10])=[O:9])=[C:6]([C:11]2[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][C:12]=2[Cl:18])[CH:5]=[CH:4][N:3]=1.[CH3:19][O:20][CH2:21][CH:22]([NH2:25])[CH2:23][CH3:24]>>[Cl:18][C:12]1[CH:13]=[C:14]([Cl:17])[CH:15]=[CH:16][C:11]=1[C:6]1[CH:5]=[CH:4][N:3]=[C:2]([NH:25][CH:22]([CH2:21][O:20][CH3:19])[CH2:23][CH3:24])[C:7]=1[N+:8]([O-:10])=[O:9]

参加物

3

反応物 2

HCID 938372-Butanamine, 1-methoxy-HCID 220521022-Chloro-4-(2,4-dichloro-phenyl)-3-nitro-pyridine

生成物 1

HCID 22052219[4-(2,4-Dichloro-phenyl)-3-nitro-pyridin-2-yl]-(1-methoxymethyl-propyl)-amine収率 88%

実験手順

2-Chloro-4-(2,4-dichloro-phenyl)-3-nitro-pyridine (0.20 g, 0.66 mmol) and 1-methoxymethyl-propylamine (0.14 g, 1.32 mmol) were treated as in Part D of Example 9 to yield 0.21 g (88%) of [4-(2,4-dichloro-phenyl)-3-nitro-pyridin-2-yl]-(1-methoxymethyl-propyl)-amine: MS (AP) m/z 370.2 [(M+H)+, 97].

出典と根拠

ORDレコード
ord-0cb88146fb7d431c84f6f9f0b98a05c9
出典データセット
uspto-grants-2006_06
特許番号
US07067658B2

関連ノート

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