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6-Aminopenicillanic acid → Carbenicillin
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 6-Aminopenicillanic acid | HCID 11082 | — |
| 反応物 | 2,2-Dimethyl-5-phenyl-1,3-dioxane-4,6-dione | HCID 84848 | — |
| 生成物 | Carbenicillin | HCID 20824 | — |
反応手順
When an equivalent amount of 2.2-tetramethylene-5-phenyl-1.3-dioxane-4.6-dione prepared in the example 3 is substituted for 2.2-dimethyl-5-phenyl-1.3-dioxane-4.6-dione and the reaction with 6-aminopenicillanic acid is carried out as disclosed in the example 1, 6-(α-carboxy-α-phenylacetamido)penicillanic acid (carbenicillin) is obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04066664 |
| 出典データセット | uspto-grants-1978_01 |
| ORD ID | ord-b18adc18aa7e45aa8288d8e5b0b1dbda |
| 出典メモ | uspto-grants-1978_01 |