HRID1833409

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC1(C)S[C@@H]2[C@H](N)C(=O)N2[C@H]1C(=O)O

HCID11082

6-Aminopenicillanic acid

C8H12N2O3S

HCID84848

2,2-Dimethyl-5-phenyl-1,3-dioxane-4,6-dione

C12H12O4

PRODUCTS

生成物

结构：CC1(C)S[C@@H]2[C@H](NC(=O)C(C(=O)O)c3ccccc3)C(=O)N2[C@H]1C(=O)O

HCID20824

Carbenicillin

C17H18N2O6S

PROCEDURE

实验过程

When an equivalent amount of 2.2-tetramethylene-5-phenyl-1.3-dioxane-4.6-dione prepared in the example 3 is substituted for 2.2-dimethyl-5-phenyl-1.3-dioxane-4.6-dione and the reaction with 6-aminopenicillanic acid is carried out as disclosed in the example 1, 6-(α-carboxy-α-phenylacetamido)penicillanic acid (carbenicillin) is obtained.