Hydrochloric Acid → 2-[(2,6-Dichloropyridin-3-yl)oxy]propanoic acid
反応式
C([O:3][C:4](=[O:16])[CH:5]([O:7][C:8]1[C:9]([Cl:15])=[N:10][C:11]([Cl:14])=[CH:12][CH:13]=1)[CH3:6])C.Cl>[OH-].[Na+]>[Cl:15][C:9]1[C:8]([O:7][CH:5]([CH3:6])[C:4]([OH:16])=[O:3])=[CH:13][CH:12]=[C:11]([Cl:14])[N:10]=1参加物
4
実験手順
105 g of 2-[(2,6-dichloro-3-pyridyl)oxy]propionic acid ethyl ester is refluxed with 550 ml of 1N sodium hydroxide solution for 1 hour. The pH value of the solution is brought to 1.5 with concentrated hydrochloric acid and the solution is filtered. Recrystallisation in ethanol/water yields 58 g of the above acid; m.p. 128°-131°;
後処理
- filtrationthe solution is filtered
- customRecrystallisation in ethanol/water
出典と根拠
- ORDレコード
- ord-341c0d58a1c7458d85c7d48bdb13b66b
- 出典データセット
- uspto-grants-1978_01
- 特許番号
- US04067725
反応ノート
読み込み中…