Sodium Hydroxide → HCID 22749369、化合物
反応式
[CH3:1][N:2]([C:18]([CH2:23][OH:24])([CH2:21][OH:22])[CH2:19][OH:20])[C:3](=[O:17])[C:4]1[CH:5]=[C:6]([CH:11]=[C:12]([N+:14]([O-:16])=[O:15])[CH:13]=1)[C:7]([O:9]C)=[O:8].[OH-].[Na+]>CO>[CH3:1][N:2]([C:18]([CH2:23][OH:24])([CH2:19][OH:20])[CH2:21][OH:22])[C:3](=[O:17])[C:4]1[CH:5]=[C:6]([CH:11]=[C:12]([N+:14]([O-:16])=[O:15])[CH:13]=1)[C:7]([OH:9])=[O:8]参加物
4
実験手順
Methyl N-methyl-5-nitro-N-[tris(hydroxymethyl)methyl]isophthalamate is stirred with one equivalent of sodium hydroxide in aqueous methanol. The reaction mixture is concentrated to remove the methanol, diluted with water and acidified with mineral acid to provide crystalline N-methyl-5-nitro-N-[tris (hydroxymethyl)methyl]isophthalamic acid.