Isobutyraldehyde → HCID 20373150、化合物

反応式

[C:1]([C:6]1[NH:7][C:8]([CH2:12][CH3:13])=[C:9]([CH3:11])[CH:10]=1)([O:3][CH2:4][CH3:5])=[O:2].[CH:14](=O)[CH:15]([CH3:17])[CH3:16]>>[C:1]([C:6]1[NH:7][C:8]([CH2:12][CH3:13])=[C:9]([CH3:11])[C:10]=1[CH2:14][CH:15]([CH3:17])[CH3:16])([O:3][CH2:4][CH3:5])=[O:2]

参加物

反応物 2

HCID 6561Isobutyraldehyde

HCID 14786498Ethyl 5-ethyl-4-methyl-1H-pyrrole-2-carboxylate

生成物 1

HCID 20373150HCID 20373150、化合物

実験手順

The crude product, obtained in Example 68 but using 2-carbethoxy-4-methyl-5-ethylpyrrole and isobutyraldehyde, solidified at 0° C. after distillation (70° C. 1 × 10-4 mm). It was recrystallized twice from methanol, m.p. 53°-55° C. (12%).

後処理

customsolidified at 0° C.
distillationafter distillation (70° C. 1 × 10-4 mm)
customIt was recrystallized twice from methanol, m.p. 53°-55° C. (12%)

出典と根拠

ORDレコード: ord-eadd17f2ba8845cea5926be6665c93b1
出典データセット: uspto-grants-1978_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04070366

反応ノート

読み込み中…

参加物