Diethyl Ether → 3,4-Dichlorobenzhydrazide
反応式
C([O:3][C:4](=O)[C:5]1[CH:10]=[CH:9][C:8]([Cl:11])=[C:7]([Cl:12])[CH:6]=1)C.O.[NH2:15][NH2:16].C(OCC)C>C(O)C>[Cl:12][C:7]1[CH:6]=[C:5]([CH:10]=[CH:9][C:8]=1[Cl:11])[C:4]([NH:15][NH2:16])=[O:3]参加物
5
実験手順
17.5g (0.08 mol) of 3,4-dichlorobenzoic ethyl ester and 4.3g (0.086 mol) of 100%-hydrazine hydrate in 30 ml of ethanol were refluxed under heat for 6.5 hours. Upon cooled, the sedimented white crystals were added with ethyl ether and the reaction mixture was enough agitated and pulverized. The thus resulted products were filtered and enough washed with ethyl ether to provide 9.3g of 3,4-dichlorobenzoic hydrazide in white crystals. m.p.: 168°-170° C. Yield: 57%.
後処理
- temperatureunder heat for 6.5 hours
- temperatureUpon cooled
- filtrationThe thus resulted products were filtered
- washenough washed with ethyl ether
出典と根拠
- ORDレコード
- ord-14e4908dcf784a8e85d7a881440363ce
- 出典データセット
- uspto-grants-1978_01
- 特許番号
- US04071633
反応ノート
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