化工社化工社 化学情報印刷レポート · 研究参考用
(3-Chlorophenyl)boronic acid → Ethyl 2-{4-[3-(3-chlorophenyl)phenoxy]phenyl}-1-cyclohexylbenzimidazole-5-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | (3-Chlorophenyl)boronic acid | HCID 2734323 | — |
| 反応物 | Ethyl 2-[4-(3-bromophenoxy)phenyl]-1-cyclohexylbenzimidazole-5-carboxylate | HCID 9914616 | — |
| 生成物 | Ethyl 2-{4-[3-(3-chlorophenyl)phenoxy]phenyl}-1-cyclohexylbenzimidazole-5-carboxylate | HCID 10231019 | 85.6% |
反応手順
Ethyl 2-[4-(3-bromophenoxy)phenyl]-1-cyclohexylbenzimidazole-5-carboxylate (65 g) obtained in Example 1 and 3-chlorophenylboronic acid (23 g) were treated in the same manner as in Example 5 to give the title compound (59 g, yield 85%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US06770666B2 |
| 出典データセット | uspto-grants-2004_08 |
| ORD ID | ord-aaf9765864a54fc4992ee6b11ecf0c70 |
| 出典メモ | uspto-grants-2004_08 |