Sodium Hydroxide → HCID 178526436、化合物

HRID 1837506ノート

反応式

HRID 1837506 の反応式
[CH2:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH2:3][CH:2]1[C:10]1[N:11]=[CH:12][NH:13][CH:14]=1.[N+:15]([O-])([OH:17])=[O:16].NC(N)=O.[OH-].[Na+]>S(=O)(=O)(O)O>[N+:15]([C:6]1[CH:5]=[C:4]2[C:9](=[CH:8][CH:7]=1)[CH2:1][CH:2]([C:10]1[N:11]=[CH:12][NH:13][CH:14]=1)[CH2:3]2)([O-:17])=[O:16]

参加物

5

反応物 3

HCID 14798Sodium HydroxideHCID 31295Urea nitrateHCID 178419880HCID 178419880、化合物

生成物 1

HCID 178526436HCID 178526436、化合物

試薬・触媒・溶媒 1

HCID 1118Sulfuric Acid溶媒

実験手順

5 g of 4-indan-2-yl-1H-imidazole are dissolved at 0° C. in 140 ml of pure sulphuric acid, and then 1 equivalent of urea nitrate in powder form is added in small portions. The reaction mixture is poured onto ice, rendered alkaline using sodium hydroxide solution and extracted with ethyl acetate. The expected product is obtained after evaporation.

後処理

  1. additionThe reaction mixture is poured onto ice
  2. extractionextracted with ethyl acetate

出典と根拠

ORDレコード
ord-699b92fbdbb54594a794bbccc449e70a
出典データセット
uspto-grants-2004_08
特許番号
US06784183B2

反応ノート

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