Uracil → Benzyl chloromethyl ether
反応式
CO[C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][C:12]=1OC)NC(=O)N[C:6]2=[O:16].N1C=CC(=O)NC1=O.C[Si](C)(C)CCO[CH2:30][Cl:31]>>[CH2:6]([O:16][CH2:30][Cl:31])[C:5]1[CH:4]=[CH:3][CH:12]=[CH:11][CH:10]=1参加物
4
実験手順
In a similar manner to the procedures described in Reference Example 3, reactions were carried out using 6,7-dimethoxyquinazoline-2,4-dione, instead of pyrimidine-2,4-dione, and using 2-(trimethylsilyl)ethoxymethyl chloride, instead of benzyloxymethyl chloride, to give the title compound (yield 93%) as a white powder.
出典と根拠
- ORDレコード
- ord-6f3d8ae2b58a41a286cadb71d0f9d0b8
- 出典データセット
- uspto-grants-2004_01
- 特許番号
- US06673804B1
反応ノート
読み込み中…