Iodoethane → 5,6-bis(4-Methoxyphenyl)-4-cyano2-ethyl-2H-pyridazin-3-one

反応式

[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][NH:12][C:11](=[O:23])[C:10]=2[C:24]#[N:25])=[CH:5][CH:4]=1.[CH2:26](I)[CH3:27]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[C:14]([C:15]3[CH:20]=[CH:19][C:18]([O:21][CH3:22])=[CH:17][CH:16]=3)=[N:13][N:12]([CH2:26][CH3:27])[C:11](=[O:23])[C:10]=2[C:24]#[N:25])=[CH:5][CH:4]=1

参加物

反応物 2

HCID 6340Iodoethane

HCID 126885835,6-bis(4-methoxyphenyl)-4-cyano-2H-pyridazin-3-one

生成物 1

HCID 98203185,6-bis(4-Methoxyphenyl)-4-cyano2-ethyl-2H-pyridazin-3-one収率 76.8%

実験手順

Using 5,6-bis(4-methoxyphenyl)-4-cyano-2H-pyridazin-3-one and ethyl iodide as starting materials, the procedures of Example 1 were repeated likewise, whereby the title compound was obtained in a yield of 76.8%.

出典と根拠

ORDレコード: ord-33e32095c7b44fab93a996e4491716fd
出典データセット: uspto-grants-2004_01
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06680316B1

反応ノート

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