Cyclohexanemethylamine → HCID 86719133、化合物
反応式
[C:1]([C:5]1[CH:6]=[C:7]([C:15](=O)[CH2:16][CH2:17][C:18](=O)[CH3:19])[CH:8]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].[CH:22]1([CH2:28][NH2:29])[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1>C1(C)C=CC=CC=1.CC1C=CC(S(O)(=O)=O)=CC=1>[CH:22]1([CH2:28][N:29]2[C:18]([CH3:19])=[CH:17][CH:16]=[C:15]2[C:7]2[CH:6]=[C:5]([C:1]([CH3:4])([CH3:3])[CH3:2])[CH:10]=[C:9]([C:11]([CH3:14])([CH3:13])[CH3:12])[CH:8]=2)[CH2:27][CH2:26][CH2:25][CH2:24][CH2:23]1参加物
5
実験手順
To a solution of 5a (6.4 g, 22.2 mmol) in toluene (100 mL) was added cyclohexylmethanamine (2.8 g, 24.4 mmol) and TsOH (0.3 g). This mixture was refluxed for 20 h, cooled, concentrated and purified by CC to afford compound 5b (7.5 g, 93%) as yellow oil.