Chlorosulfonic acid → 5-(Chlorosulfonyl)-3-iodo-2-methylbenzoic acid
反応式
[Cl:1][S:2]([OH:5])(=O)=[O:3].[I:6][C:7]1[C:8]([CH3:16])=[C:9]([CH:13]=[CH:14][CH:15]=1)[C:10]([OH:12])=[O:11]>>[Cl:1][S:2]([C:14]1[CH:15]=[C:7]([I:6])[C:8]([CH3:16])=[C:9]([CH:13]=1)[C:10]([OH:12])=[O:11])(=[O:5])=[O:3]参加物
3
反応条件
- 温度
- 95 °C
実験手順
A round bottom flask was charged with chlorosulfonic acid (3.80 mL, 57.2 mmol), and 3-iodo-2-methylbenzoic acid (5.00 g, 19.1 mmol) was added in portions at 0° C. The reaction was heated at 95° C. for two hours and then stirred at room temperature overnight. The reaction mixture was poured onto ice and the solids formed were collected and dried to afford the desired product as a white solid.
後処理
- additionwas added in portions at 0° C
- additionThe reaction mixture was poured onto ice
- customthe solids formed
- customwere collected
- customdried
出典と根拠
- ORDレコード
- ord-7e4ff6ddcfeb45ef81acbef820676750
- 出典データセット
- uspto-grants-2015_02
- 特許番号
- US08946439B2
反応ノート
読み込み中…