m-Chloroperbenzoic acid → 2-(2-Phenylethyl)oxirane

HRID 1845346

反応式

HRID 1845346 の反応式
ClC1C=C(C(OO)=[O:9])C=CC=1.[CH:12]([C:16]1[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=1)=[CH:13][CH2:14][CH3:15].C([O-])(O)=O.[Na+]>C(Cl)Cl>[C:16]1([CH2:12][CH2:13][CH:14]2[CH2:15][O:9]2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

参加物

5

反応物 3

HCID 70297m-Chloroperbenzoic acidHCID 1230881-Phenyl-1-buteneHCID 516892Sodium Bicarbonate

生成物 1

HCID 1359552-(2-Phenylethyl)oxirane

試薬・触媒・溶媒 1

HCID 6344Dichloromethane溶媒

反応条件

温度
25 °C

実験手順

3-chlorobenzenecarboperoxoic acid (12.1 g, 54.0 mmol) is added in one portion to a solution of 3-buten-1-ylbenzene (7.15 g, 54.1 mmol) in CH2Cl2 at 0° C. followed by warming to 25° C. overnight. Saturated NaHCO3 was added and the mixture separated and the resulting clear oil (8.0 g, quant.) was carried forward without further purification: LC-MS (ES) m/z=149 (M+H)+.

後処理

  1. customthe mixture separated
  2. customthe resulting clear oil (8.0 g, quant.) was carried forward without further purification

出典と根拠

ORDレコード
ord-5bf19ada55e14286bd729bb566c09e75
出典データセット
uspto-grants-2015_02
特許番号
US08946278B2

関連ノート

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