Diethyl Ether → 4-chloro-5,8-difluoro-N-(4-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)phthalazin-1-amine

反応式

[C:37]([OH:38])([CH3:39])([CH3:40])[CH3:41].[CH3:42][CH2:43][O:44][CH2:45][CH3:46].[Cl:23][c:24]1[n:25][n:26][c:27]([Cl:36])[c:28]2[c:29]([F:35])[cH:30][cH:31][c:32]([F:34])[c:33]12.[NH2:1][c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[n:8][cH:9][cH:10][cH:11][c:12]2-[c:13]2[n:14][c:15]([NH:19][CH3:20])[n:16][cH:17][cH:18]2)[cH:21][cH:22]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([O:6][c:7]2[n:8][cH:9][cH:10][cH:11][c:12]2-[c:13]2[n:14][c:15]([NH:19][CH3:20])[n:16][cH:17][cH:18]2)[cH:21][cH:22]1)[c:27]1[n:26][n:25][c:24]([Cl:23])[c:33]2[c:28]1[c:29]([F:35])[cH:30][cH:31][c:32]2[F:34]