Iodoethane → (4-Ethylmorpholin-3-yl)methanol
反応式
[NH:1]1[CH2:6][CH2:5][O:4][CH2:3][CH:2]1[CH2:7][OH:8].I[CH2:10][CH3:11].C([O-])([O-])=O.[K+].[K+]>CN(C)C=O.O>[CH2:10]([N:1]1[CH2:6][CH2:5][O:4][CH2:3][CH:2]1[CH2:7][OH:8])[CH3:11]参加物
6
実験手順
Morpholin-3-ylmethanol (500 mg) and iodoethane (666 mg) in N,N-dimethylformamide was treated with K2CO3 (1.1 g) overnight. The reaction mixture was diluted with water and extracted with ethyl acetate. The organic layer was dried over Na2SO4 and concentrated to provide the title compound.
後処理
- extractionextracted with ethyl acetate
- dry with materialThe organic layer was dried over Na2SO4
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-de12b76ba68a4f9cae36268324e75ce0
- 出典データセット
- uspto-grants-2015_02
- 特許番号
- US08952157B2
反応ノート
読み込み中…