3,5-Diamino-1,2,4-triazole → HCID 178508251、化合物

HRID 1851217

反応式

HRID 1851217 の反応式
[NH2:1][C:2]1[N:6]=[C:5]([NH2:7])[NH:4][N:3]=1.[C:8]1([CH:14]([C:20](OCC)=[O:21])[C:15](OCC)=[O:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>C(N(CCCC)CCCC)CCC>[NH2:1][C:2]1[N:6]=[C:5]2[N:7]=[C:15]([OH:16])[C:14]([C:8]3[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=3)=[C:20]([OH:21])[N:4]2[N:3]=1

参加物

4

反応物 2

HCID 150783,5-Diamino-1,2,4-triazoleHCID 66514Diethyl phenylmalonate

生成物 1

HCID 178508251HCID 178508251、化合物

試薬・触媒・溶媒 1

HCID 7622Tributylamine溶媒

実験手順

A solution of 9.0 g 3,5-diamino-1,2,4-triazole and 22.4 mL diethyl phenylmalonate in N,N-dibutylbutan-1-amine was heated under microwave irradiation to 180° C. for 8 h. The reaction mixture formed two layers after cooling to room temperature. The top layer was removed and the solvent of the lower layer was evaporated. The residue was treated with water and acidified with 5N HCl. The precipitated product was collected by filtration and dried. The crude product was used without further purification.

後処理

  1. customThe reaction mixture formed two layers
  2. customThe top layer was removed
  3. customthe solvent of the lower layer was evaporated
  4. additionThe residue was treated with water
  5. filtrationThe precipitated product was collected by filtration
  6. customdried
  7. customThe crude product was used without further purification

出典と根拠

ORDレコード
ord-66d812d7ed2d46ae9b8c90c93a1783d1
出典データセット
uspto-grants-2015_02
特許番号
US08957064B2

関連ノート

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