HCID 178498471、化合物 → Methyl 5-amino-1H-pyrazole-3-carboxylate

HRID 1851230ノート

反応式

HRID 1851230 の反応式
[N+:1]([C:4]1[CH:8]=[C:7]([C:9]([O:11][CH3:12])=[O:10])[NH:6][N:5]=1)([O-])=O>CO.[Pd]>[NH2:1][C:4]1[CH:8]=[C:7]([C:9]([O:11][CH3:12])=[O:10])[NH:6][N:5]=1

参加物

4

反応物 1

HCID 178498471HCID 178498471、化合物

生成物 1

HCID 18445864Methyl 5-amino-1H-pyrazole-3-carboxylate

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 887Methanol溶媒

実験手順

To 14.0 g methyl 3-nitro-1H-pyrazole-5-carboxylate in 200 mL methanol were added 1.2 g Pd/C (10% w/w). The mixture was stirred under H2-atmosphere at room temperature for 18 h. The mixture was filtered through Celite. The filtrate was concentrated and the crude product was used without further purification.

後処理

  1. filtrationThe mixture was filtered through Celite
  2. concentrationThe filtrate was concentrated
  3. customthe crude product was used without further purification

出典と根拠

ORDレコード
ord-81fc562003f548ffa06cdd3904f5e467
出典データセット
uspto-grants-2015_02
特許番号
US08957064B2

反応ノート

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