Diisopropylethylamine → (2S,4R)-tert-butyl 2-(((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)carbamoyl)-4-((4-methoxyisoquinolin-1-yl)oxy)pyrrolidine-1-carboxylate

反応式

[C:1]([O:5][C:6]([N:8]1[CH2:12][C@H:11]([O:13][C:14]2[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[C:17]([O:24][CH3:25])=[CH:16][N:15]=2)[CH2:10][C@H:9]1[C:26](O)=[O:27])=[O:7])([CH3:4])([CH3:3])[CH3:2].CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.CCN(C(C)C)C(C)C.Cl.[NH2:63][C@:64]1([C:69]([NH:71][S:72]([CH:75]2[CH2:77][CH2:76]2)(=[O:74])=[O:73])=[O:70])[CH2:66][C@H:65]1[CH:67]=[CH2:68]>ClCCl>[CH:75]1([S:72]([NH:71][C:69]([C@@:64]2([NH:63][C:26]([C@@H:9]3[CH2:10][C@@H:11]([O:13][C:14]4[C:23]5[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=5)[C:17]([O:24][CH3:25])=[CH:16][N:15]=4)[CH2:12][N:8]3[C:6]([O:5][C:1]([CH3:2])([CH3:3])[CH3:4])=[O:7])=[O:27])[CH2:66][C@H:65]2[CH:67]=[CH2:68])=[O:70])(=[O:74])=[O:73])[CH2:77][CH2:76]1