909135-23-5 → HCID 59193687、化合物
反応式
I[C:2]1[C:7]([CH3:8])=[C:6]([CH3:9])[CH:5]=[CH:4][C:3]=1[N+:10]([O-:12])=[O:11]>CN(C=O)C.[Cu]>[CH3:8][C:7]1[C:6]([CH3:9])=[CH:5][CH:4]=[C:3]([N+:10]([O-:12])=[O:11])[C:2]=1[C:2]1[C:3]([N+:10]([O-:12])=[O:11])=[CH:4][CH:5]=[C:6]([CH3:9])[C:7]=1[CH3:8]参加物
4
実験手順
In 20 ml of a DMF solvent, 5.5 g (20 mmol) of 2-iodo-3,4-dimethyl-1-nitrobenzene and 10 g (155 mmol) of copper powder were heated at 150° C. for 48 hours. After the completion of the reaction, copper powder was removed by filtration and thereafter, the resultant was extracted using ethyl acetate, dried/concentrated, and then purified by column chromatography (ethyl acetate:hexane=1:10) to obtain 2.9 g (0.96 mmol) of 2,3,2′,3′-tetramethyl-6,6′-dinitrobiphenyl (34) (yield was 96%).
後処理
- customwas removed by filtration
- extractionthe resultant was extracted
- concentrationdried/concentrated
- custompurified by column chromatography (ethyl acetate:hexane=1:10)
出典と根拠
- ORDレコード
- ord-e1c8ee4e11a448788f5cd1f305946643
- 出典データセット
- uspto-grants-2015_02
- 特許番号
- US08962898B2
反応ノート
読み込み中…