Phthalic Anhydride → N-Methylphthalimide

HRID 1855930ノート

反応式

HRID 1855930 の反応式
O([C:8]1[CH:9]=[C:10]2[C:15](=[O:16])[N:14]([CH3:17])[C:12](=[O:13])[C:11]2=[CH:18][CH:19]=1)C1C=CC=CC=1.C1(=O)OC(=O)C2=CC=CC=C12>>[CH3:17][N:14]1[C:12](=[O:13])[C:11]2=[CH:18][CH:19]=[CH:8][CH:9]=[C:10]2[C:15]1=[O:16]

参加物

3

反応物 2

HCID 6811Phthalic AnhydrideHCID 8215562-methyl-5-phenoxyisoindole-1,3-dione

生成物 1

HCID 11074N-Methylphthalimide収率 46%

実験手順

The above results show that an exchange occurred between 4-phenoxy-N-methylphthalimide and phthalic anhydride, resulting in a 46% yield of N-methylphthalimide and a 64% yield of 4-phenoxyphthalic anhydride or acid. This conversion of 4-phenoxy-N-methylphthalimide to 4-phenoxyphthalic anhydride was achieved in a direct manner without any requirement for converting the 4-phenoxy-N-methylphthalimide to the corresponding hydrazide or the base hydrolysis thereof, resulting in the production of metal salt requiring the neutralization and heating of the resulting phthalic acid.

後処理

  1. customThe above results

出典と根拠

ORDレコード
ord-796184338a7c4165a53017e35c02ff7c
出典データセット
uspto-grants-1980_08
特許番号
US04217281

反応ノート

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