HCID 54095087、化合物 → 2-(4-Aminobutanamido)ethane-1-sulfonic acid

HRID 1856146ノート

反応式

HRID 1856146 の反応式
C([N:11]([C:18](=[O:23])[CH2:19][CH2:20][CH2:21][NH2:22])[CH2:12][CH2:13][S:14]([OH:17])(=[O:16])=[O:15])(OCC1C=CC=CC=1)=O>O.[Pd]>[NH2:22][CH2:21][CH2:20][CH2:19][C:18]([NH:11][CH2:12][CH2:13][S:14]([OH:17])(=[O:15])=[O:16])=[O:23]

参加物

4

反応物 1

HCID 54095087HCID 54095087、化合物

生成物 1

HCID 131463522-(4-Aminobutanamido)ethane-1-sulfonic acid収率 76%

試薬・触媒・溶媒 2

HCID 23938Palladium触媒HCID 962Water溶媒

実験手順

The N-carbobenzoxy-γ-aminobutyryl-taurine obtained as described in Example 2 is dissolved in 10 ml of water. 100 mg of 10% palladium-on-carbon catalyst are added to the solution, and the mixture is hydrogenated for 2 hours. The catalyst is filtered off, and the filtrate is evaporated in vacuo at 35° C. The obtained crude product is crystallized from a 1:10 mixture of water and acetone. 0.798 g (76%) of γ-aminobutyryl-taurine are obtained: m.p.: 247° C.

後処理

  1. filtrationThe catalyst is filtered off
  2. customthe filtrate is evaporated in vacuo at 35° C
  3. customThe obtained crude product
  4. customis crystallized from a 1:10 mixture of water and acetone

出典と根拠

ORDレコード
ord-f84eeb162e0d49b49cff729b68a0fef9
出典データセット
uspto-grants-1980_08
特許番号
US04218404

反応ノート

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