Trifluoroacetic acid → HCID 22122160、化合物
反応式
[N:1]([CH2:4][CH2:5][N:6]1[CH2:11][CH2:10][N:9](CC2C=CC(OC)=CC=2OC)[C:8](=[O:23])[C:7]1=[O:24])=[N+:2]=[N-:3].FC(F)(F)C(O)=O.C1(OC)C=CC=CC=1>>[N:1]([CH2:4][CH2:5][N:6]1[CH2:11][CH2:10][NH:9][C:8](=[O:23])[C:7]1=[O:24])=[N+:2]=[N-:3]参加物
4
実験手順
A mixture of 3.65 g of 1-(2-azidoethyl)-4-(2,4-dimethoxybenzyl)-2,3-dioxopiperazine, 14.6 ml of trifluoroacetic acid and 7.3 ml of anisole was refluxed for 2 hours. The solvent was distilled off under reduced pressure and the resulting residue was purified by a silica gel column chromatography (eluent; chloroform:methanol=20:1) to obtain 1.8 g of 1-(2-azidoethyl)-2,3-dioxopiperazine as an oil.
後処理
- temperaturewas refluxed for 2 hours
- distillationThe solvent was distilled off under reduced pressure
- customthe resulting residue was purified by a silica gel column chromatography (eluent; chloroform:methanol=20:1)
出典と根拠
- ORDレコード
- ord-de2715a7631f4703a24381749a8306dc
- 出典データセット
- uspto-grants-2000_11
- 特許番号
- US06153613
反応ノート
読み込み中…