HCID 53778251、化合物 → 4-Methyl-1-pyridin-4-yl-pentan-3-one
反応式
[CH3:1][CH:2]([CH3:13])[C:3](=[O:12])[CH:4]=[CH:5][C:6]1[CH:11]=[CH:10][N:9]=[CH:8][CH:7]=1>C1COCC1>[CH3:1][CH:2]([CH3:13])[C:3](=[O:12])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][N:9]=[CH:8][CH:7]=1参加物
3
実験手順
The title compound was prepared according to General Method 3 using 4-methyl-1-pyridin-4-yl-pent-1-en-3-one (Example B-16; 1.81 g), (Ph3P)3RhCl (0.5 g), and THF (100 mL) at 50 psi. The title compound was flash chromatographed using 98:2 CH2Cl2:MeOH as eluent. 1H NMR (CDCl3): δ1.15 (d, 6 H), 2.5-2.7 (m, 1 H), 2.7-2.8 (m, 2 H), 2.85-2.95 (m, 2 H), 7.1 (d, 2 H), 8.5 (d, 2 H).
後処理
- customThe title compound was prepared
- customchromatographed
出典と根拠
- ORDレコード
- ord-9c7ec8ee832c42cca44fd8981f667ba7
- 出典データセット
- uspto-grants-2003_03
- 特許番号
- US06528510B1
反応ノート
読み込み中…