Ethyl 3-[4-(2-azidoethoxy)phenyl]-2-butylpropionate → Ethyl 3-[4-(2-aminoethoxy)phenyl]-2-butylpropionate
反応式
[N:1]([CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH:14]([CH2:20][CH2:21][CH2:22][CH3:23])[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:9][CH:8]=1)=[N+]=[N-]>[Pd]>[NH2:1][CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([CH2:13][CH:14]([CH2:20][CH2:21][CH2:22][CH3:23])[C:15]([O:17][CH2:18][CH3:19])=[O:16])=[CH:9][CH:8]=1参加物
3
実験手順
In a similar manner to that described in Reference example 1(d), a reaction was carried out using ethyl 3-[4-(2-azidoethoxy)phenyl]-2-butylpropionate (1.62 g), which is the product of Reference example 6(g), and palladium on carbon (5%, 243 mg) and the reaction mixture was treated to afford the title compound (1.49 g) as a syrup.
後処理
- additionthe reaction mixture was treated