Sodium Hydroxide → 4'-Dimethoxymethylbiphenyl-4-carboxylic acid

HRID 1860008ノート

反応式

HRID 1860008 の反応式
[CH3:1][O:2][CH:3]([O:20][CH3:21])[C:4]1[CH:9]=[CH:8][C:7]([C:10]2[CH:15]=[CH:14][C:13]([C:16]([O:18]C)=[O:17])=[CH:12][CH:11]=2)=[CH:6][CH:5]=1.[OH-].[Na+]>>[CH3:21][O:20][CH:3]([O:2][CH3:1])[C:4]1[CH:5]=[CH:6][C:7]([C:10]2[CH:15]=[CH:14][C:13]([C:16]([OH:18])=[O:17])=[CH:12][CH:11]=2)=[CH:8][CH:9]=1

参加物

3

反応物 2

HCID 14798Sodium HydroxideHCID 18625704Methyl 4'-dimethoxymethylbiphenyl-4-carboxylate

生成物 1

HCID 186256964'-Dimethoxymethylbiphenyl-4-carboxylic acid収率 100.1%

実験手順

In a similar manner to that described in Example 2, a reaction was carried out using methyl 4′-dimethoxymethylbiphenyl-4-carboxylate (1.89 g), which is the product of Reference example 11(a), and aqueous sodium hydroxide (1N, 9.90 ml) and the reaction mixture was treated to afford the desired compound (1.80 g) as colorless crystals.

後処理

  1. additionthe reaction mixture was treated

出典と根拠

ORDレコード
ord-082edb70c69f4c4d9be86f4b0f653062
出典データセット
uspto-grants-2003_03
特許番号
US06528525B1

反応ノート

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