Sodium Hydroxide → 4-(2-hydroxyphenyl)benzoic Acid

HRID 1860020ノート

反応式

HRID 1860020 の反応式
[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][C:11]([C:14]([O:16]C)=[O:15])=[CH:10][CH:9]=1.[OH-].[Na+]>>[OH:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[CH:13]=[CH:12][C:11]([C:14]([OH:16])=[O:15])=[CH:10][CH:9]=1

参加物

3

反応物 2

HCID 14798Sodium HydroxideHCID 45648562-(4-Methoxycarbonylphenyl)phenol

生成物 1

HCID 106562444-(2-hydroxyphenyl)benzoic Acid収率 92.9%

実験手順

In a similar manner to that described in Example 2, a reaction was carried out using methyl 2′-hydroxybiphenyl-4-carboxylate (498 mg) and aqueous sodium hydroxide (1N, 4.81 ml) and the reaction mixture was treated to afford the title compound (434 mg) as colorless crystals.

後処理

  1. additionthe reaction mixture was treated

出典と根拠

ORDレコード
ord-340d1ef9824643168ccac76c4eb8a5ab
出典データセット
uspto-grants-2003_03
特許番号
US06528525B1

反応ノート

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