Sodium Hydroxide → 4'-Methoxymethoxy-3',5'-dimethylbiphenyl-4-carboxylic acid

反応式

[CH3:1][O:2][CH2:3][O:4][C:5]1[C:10]([CH3:11])=[CH:9][C:8]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([O:20]C)=[O:19])=[CH:14][CH:13]=2)=[CH:7][C:6]=1[CH3:22].[OH-].[Na+]>>[CH3:1][O:2][CH2:3][O:4][C:5]1[C:10]([CH3:11])=[CH:9][C:8]([C:12]2[CH:17]=[CH:16][C:15]([C:18]([OH:20])=[O:19])=[CH:14][CH:13]=2)=[CH:7][C:6]=1[CH3:22]

参加物

反応物 2

HCID 14798Sodium Hydroxide

HCID 18625974Methyl 4'-methoxymethoxy-3',5'-dimethylbiphenyl-4-carboxylate

生成物 1

HCID 186257084'-Methoxymethoxy-3',5'-dimethylbiphenyl-4-carboxylic acid収率 83.7%

実験手順

In a similar manner to that described in Example 2, a reaction was carried out using methyl 4′-methoxymethoxy-3′,5′-dimethylbiphenyl-4-carboxylate (1.24 g) and aqueous sodium hydroxide (1N, 8.20 ml) and the reaction mixture was treated to afford the desired compound (0.99 g) as colorless crystals.

後処理

additionthe reaction mixture was treated

出典と根拠

ORDレコード: ord-eb415a7c1833460a88234ec39342e51a
出典データセット: uspto-grants-2003_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06528525B1

反応ノート

読み込み中…

参加物