HCID 18619274、化合物 → HCID 18619216、化合物
反応式
C([O:8][C:9]1[C:10]([O:15][CH2:16][C:17]([O:19][CH3:20])=[O:18])=[N:11][CH:12]=[N:13][CH:14]=1)C1C=CC=CC=1>[Pd].C(OCC)(=O)C>[OH:8][C:9]1[C:10]([O:15][CH2:16][C:17]([O:19][CH3:20])=[O:18])=[N:11][CH:12]=[N:13][CH:14]=1参加物
4
実験手順
A mixture of 0.9 g of 5-benzyloxy-4-(methoxycarbonyl)methoxypyrimidine, 10% palladium/carbon and ethyl acetate was stirred for 3 hours at room temperature under hydrogen atmosphere. The reaction system was purged with nitrogen, then, the reaction solution was filtrated through Celite, and the filtrate was concentrated to obtain 0.574 g of 5-hydroxy-4-(methoxycarbonyl)methoxypyrimidine.
後処理
- customThe reaction system was purged with nitrogen
- filtrationthe reaction solution was filtrated through Celite
- concentrationthe filtrate was concentrated
出典と根拠
- ORDレコード
- ord-58ebe2121bf243a9ad3a7de95fb5fff0
- 出典データセット
- uspto-grants-2003_03
- 特許番号
- US06537948B1
反応ノート
読み込み中…