Hydrochloric Acid → 2-{4-[2-(4-Fluoro-phenoxy)-ethoxy]-3-methoxy-phenyl}-ethylamine hydrochloride

HRID 1862499

反応式

[F:1][C:2]1[CH:22]=[CH:21][C:5]([O:6][CH2:7][CH2:8][O:9][C:10]2[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][NH2:18])=[CH:12][C:11]=2[O:19][CH3:20])=[CH:4][CH:3]=1.[ClH:23]>C(OCC)C>[ClH:23].[F:1][C:2]1[CH:3]=[CH:4][C:5]([O:6][CH2:7][CH2:8][O:9][C:10]2[CH:15]=[CH:14][C:13]([CH2:16][CH2:17][NH2:18])=[CH:12][C:11]=2[O:19][CH3:20])=[CH:21][CH:22]=1

参加物

実験手順

To 2-{4-[2-(4-fluoro-phenoxy)-ethoxy]-3-methoxy-phenyl}-ethylamine (15.7 g) dissolved in diethylether (200 ml) is added 1M hydrogen chloride solution in diethylether (75 ml). The resulting residue is isolated by separation in a centrifuge and decantation. 2-{4-[2-(4-Fluoro-phenoxy)-ethoxy]-3-methoxy-phenyl}-ethylamine hydrochloride is obtained.

後処理

customThe resulting residue is isolated by separation in a centrifuge and decantation

出典と根拠

ORDレコード: ord-99ff543ae35a4990937d41086295e352
出典データセット: uspto-grants-2003_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06538016B2

反応式

参加物

反応物 2

生成物 1

試薬・触媒・溶媒 1

実験手順

後処理

出典と根拠

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