Isopropylamine → N-Isopropyl-4-nitro-2-(trifluoromethyl)aniline
反応式
[F:1][C:2]([F:14])([F:13])[C:3]1[CH:4]=[C:5]([N+:10]([O-:12])=[O:11])[CH:6]=[CH:7][C:8]=1Cl.[CH:15]([NH2:18])([CH3:17])[CH3:16]>CS(C)=O>[CH:15]([NH:18][C:8]1[CH:7]=[CH:6][C:5]([N+:10]([O-:12])=[O:11])=[CH:4][C:3]=1[C:2]([F:14])([F:13])[F:1])([CH3:17])[CH3:16]参加物
4
実験手順
To a solution of 45 g of 3-(trifluoromethyl)-4-chloronitrobenzene in 150 ml of DMSO was added 13 g of isopropylamine. The mixture was heated at 80°-90° C. for two hours, poured over ice water, acidified and filtered. The filter cake was dried to yield 49.6 g of product; m.p. 35°-36° C.
後処理
- temperatureThe mixture was heated at 80°-90° C. for two hours
- filtrationfiltered
- customThe filter cake was dried
出典と根拠
- ORDレコード
- ord-53e8b43e3737455abc120b80728ee359
- 出典データセット
- uspto-grants-1979_09
- 特許番号
- US04168153
反応ノート
読み込み中…