Methanol → Dimethyl phenylphosphonite

HRID 1863194

反応式

HRID 1863194 の反応式
[CH3:1][OH:2].C(N(CC)CC)C.[C:10]1([P:16](Cl)Cl)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.CC[O:21][CH2:22]C>>[CH3:1][O:2][P:16]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[O:21][CH3:22]

参加物

5

反応物 4

HCID 887MethanolHCID 3283Diethyl EtherHCID 8471TriethylamineHCID 12573Phenyl phosphorus dichloride

生成物 1

HCID 76277Dimethyl phenylphosphonite

実験手順

Methanol (12.8 gm., 0.4 mol.) and triethylamine (40.4 gm., 0.4 mol.) are dissolved in 750 ml. ether and chilled in an ice bath. Phenyl dichlorophosphine (35.8 gm., 0.2 mol.) is added dropwise and the reaction mixture is stirred overnight. The resulting suspension is filtered and the filtrate concentrated to an oil which is distilled in vacuo to give the product, phenylphosphonous acid dimethyl ester, b.p. 100°-105° /10 mm; yield 20 gm. (59%).

後処理

  1. filtrationThe resulting suspension is filtered
  2. concentrationthe filtrate concentrated to an oil which
  3. distillationis distilled in vacuo

出典と根拠

ORDレコード
ord-f00fb573abdc4100a89c6b889344fbbd
出典データセット
uspto-grants-1979_09
特許番号
US04168267

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