Cyanuric chloride → 4,6-Dichloro-N-(4-ethenylphenyl)-1,3,5-triazin-2-amine

HRID 1863358ノート

反応式

HRID 1863358 の反応式
[N:1]1[C:8]([Cl:9])=[N:7][C:5]([Cl:6])=[N:4][C:2]=1Cl.[CH:10]([C:12]1[CH:18]=[CH:17][C:15]([NH2:16])=[CH:14][CH:13]=1)=[CH2:11].C(N(CC)C(C)C)(C)C>CC(C)=O>[CH:10]([C:12]1[CH:18]=[CH:17][C:15]([NH:16][C:2]2[N:1]=[C:8]([Cl:9])[N:7]=[C:5]([Cl:6])[N:4]=2)=[CH:14][CH:13]=1)=[CH2:11]

参加物

5

反応物 3

HCID 7954Cyanuric chlorideHCID 737004-AminostyreneHCID 81531Diisopropylethylamine

生成物 1

HCID 203375874,6-Dichloro-N-(4-ethenylphenyl)-1,3,5-triazin-2-amine

試薬・触媒・溶媒 1

HCID 180Acetone溶媒

実験手順

To a solution of 18.4 g. (0.1 mole) of cyanuric chloride in 150 ml. of acetone being stirred at 0°-5° C. was added dropwise over a 1/2 hr. period a solution of 11.9 g. (0.1 mole) of 4-vinylaniline and 12.9 g. (0.1 mole) of N,N-di-iso-propylethylamine. After the addition was complete, the solution was stirred at room temperature for 15 min., and then poured into 1 liter of ice water to isolate the product. The product was collected by filtration, washed with 200 ml. of water, and dried in vacuo at room temperature to give 25 g. Recrystallization from 75 ml. of benzene gave 15.0 g. (56%) (mp 152°-154°).

後処理

  1. additionwas added dropwise over a 1/2 hr
  2. additionAfter the addition
  3. customto isolate the product
  4. filtrationThe product was collected by filtration
  5. washwashed with 200 ml
  6. dry with materialof water, and dried in vacuo at room temperature
  7. customto give 25 g
  8. customRecrystallization from 75 ml
  9. customof benzene gave 15.0 g

出典と根拠

ORDレコード
ord-511d1d62c08440b78236c33151afd931
出典データセット
uspto-grants-1979_09
特許番号
US04168976

反応ノート

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