Oxaprozin → Butanedioic acid;bis(2-hydroxy-1,2-diphenylethanone)

HRID 1870491

反応式

HRID 1870491 の反応式
C1(C2N=[C:9]([CH2:18][CH2:19][C:20]([OH:22])=[O:21])[O:10]C=2C2C=CC=CC=2)C=CC=CC=1.[C:23]1([C:29]([CH:31]([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[OH:32])=[O:30])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1.C1(=O)OC(=O)CC1>>[C:20]([OH:22])(=[O:21])[CH2:19][CH2:18][C:9]([OH:30])=[O:10].[C:23]1([C:29]([CH:31]([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[OH:32])=[O:30])[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1.[C:23]1([C:29]([CH:31]([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=2)[OH:32])=[O:30])[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=1

参加物

4

反応物 3

HCID 4614OxaprozinHCID 7922Succinic anhydrideHCID 8400Benzoin

生成物 1

HCID 131711721Butanedioic acid;bis(2-hydroxy-1,2-diphenylethanone)

実験手順

A process for the preparation of 4,5-diphenyloxazole-2-propanoic acid of formula I ##STR2## by esterification of benzoin with succinic anhydride to give benzoin hemisuccinate, and cyclization to (I) by direct addition of ammonium acetate or urea to the mixture containing the hemisuccinate,

出典と根拠

ORDレコード
ord-cf112545ea7f4486bef9bbf657337f54
出典データセット
uspto-grants-2000_08
特許番号
US06096896

関連ノート

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