Ethanol → 4-(4-(Pyridin-3-yl)-1H-imidazol-1-yl)butan-1-amine

反応式

[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:8]=[CH:9][N:10]([CH:12](CC)[CH2:13]N3C(=O)C4C(=CC=CC=4)C3=O)[CH:11]=2)[CH:2]=1.O.[NH2:28]N.[CH2:30](O)[CH3:31]>>[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]2[N:8]=[CH:9][N:10]([CH2:12][CH2:13][CH2:30][CH2:31][NH2:28])[CH:11]=2)[CH:2]=1

参加物

反応物 3

HCID 702Ethanol

HCID 24654Hydrazine hydrate (1:1)

HCID 186948072-(4-(3-pyridinyl)-1H-imidazol-1-yl)-butyl-1H-iso-indol-1,3(2H)-dione

生成物 1

HCID 110421604-(4-(Pyridin-3-yl)-1H-imidazol-1-yl)butan-1-amine

実験手順

Using the procedure of Stage B of Example 1, 1.66 g of the product of Stage A and 0.46 ml of hydrazine hydrate in 30 ml of ethanol were reacted to obtain 936 mg of the desired product which was used as is for the synthesis.

後処理

customwere reacted

出典と根拠

ORDレコード: ord-bbe848dded124a9bb9282cb9a3de561e
出典データセット: uspto-grants-2000_08
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US06100404

反応ノート

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