反応式
[O:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[CH2:6][S:7][C:8]1[CH:13]=[CH:12][N:11]=[C:10]([CH2:14]O)[C:9]=1[O:16][CH3:17].[Cl:18]C1C=C[N+]([O-])=C(C)C=1OC.S(Cl)([Cl:31])=O>>[ClH:18].[Cl:31][CH2:14][C:10]1[C:9]([O:16][CH3:17])=[C:8]([S:7][CH2:6][C:2]2[O:1][CH:5]=[CH:4][CH:3]=2)[CH:13]=[CH:12][N:11]=1参加物
4
実験手順
By the procedure described in Aa) to Ac), the intermediate product 4-(2-furylmethylthio)-2-hydroxymethyl-3-methoxypyridine is obtained starting from 4-chloro-3-methoxy-2-methylpyridine N-oxide; m.p. 56-58° C. Chlorination with thionyl chloride by the procedure described in Example Ad) gives the title compound as a beige powder; m.p. 135° C. (decomp.).
後処理
- customis obtained
出典と根拠
- ORDレコード
- ord-e4fbdba7487e4460914c6af1618f1843
- 出典データセット
- uspto-grants-2000_08
- 特許番号
- US06107312
関連ノート
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