Hydrogen Bromide → 5-Bromo-5-octylbarbituric acid
反応式
[CH2:1]([CH:9]1[C:14](=[O:15])[NH:13][C:12](=[O:16])[NH:11][C:10]1=[O:17])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[BrH:18]>O>[Br:18][C:9]1([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8])[C:14](=[O:15])[NH:13][C:12](=[O:16])[NH:11][C:10]1=[O:17]参加物
4
反応条件
- 温度
- 2.5 °C
実験手順
To a suspension of 5-octylbarbituric acid (20 g) in 120 ml of water, cooled at 0-5° C., are added 12 ml of 48% hydrobromic acid and successively are dropped 4.72 ml of brornine. After 2 hours under stirring, the white solid which separated is recovered by filtration, washed with water and partitioned between 200 ml of diethyl ether and 100 ml of water.
後処理
- customthe white solid which separated
- filtrationis recovered by filtration
- washwashed with water
- custompartitioned between 200 ml of diethyl ether and 100 ml of water
出典と根拠
- ORDレコード
- ord-c7be68df5b024a02adaacf576eaed03d
- 出典データセット
- uspto-grants-2000_08
- 特許番号
- US06110924
反応ノート
読み込み中…