Acetonitrile → (2,3-Dichlorophenyl)oxoacetonitrile

HRID 1873058ノート

反応式

HRID 1873058 の反応式
[Cu]([C:4]#[N:5])C#N.C(#N)C.[Cl:9][C:10]1[C:18]([Cl:19])=[CH:17][CH:16]=[CH:15][C:11]=1[C:12](Cl)=[O:13]>C1(C)C=CC=CC=1>[Cl:19][C:18]1[C:10]([Cl:9])=[C:11]([CH:15]=[CH:16][CH:17]=1)[C:12]([C:4]#[N:5])=[O:13]

参加物

5

反応物 3

HCID 6342AcetonitrileHCID 179442,3-Dichlorobenzoyl chlorideHCID 178418260HCID 178418260、化合物

生成物 1

HCID 2735968(2,3-Dichlorophenyl)oxoacetonitrile

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒2 回

実験手順

In a mixture of 128 gm. of copper cyanide, 120 ml. of acetonitrile and 200 ml. of toluene, the solution of 200 gm. of 2,3-dichlorobenzoylchloride (II) in 250 ml of toluene was added. The reaction mixture was refluxed for 16 hour. After filtration, the solvent was removed under reduced pressure to give 200 ml of oily 2,3-dichlorobenzoyl cyanide (III).

後処理

  1. additionIn a mixture of 128 gm
  2. temperatureThe reaction mixture was refluxed for 16 hour
  3. filtrationAfter filtration
  4. customthe solvent was removed under reduced pressure

出典と根拠

ORDレコード
ord-eb095ba3eead4a9f8d3860a8dd5e9174
出典データセット
uspto-grants-2000_08
特許番号
US06111101

反応ノート

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