反応式
[NH2:1][C:2]1[N:7]=[CH:6][C:5]([O:8][C:9]2[CH:10]=[C:11]([NH:16][C:17]([C:19]3[N:23]([CH3:24])[N:22]=[C:21]([CH3:25])[CH:20]=3)=[O:18])[CH:12]=[C:13]([CH3:15])[CH:14]=2)=[CH:4][CH:3]=1.[C:26]1([CH3:36])[CH:31]=[CH:30][C:29]([S:32](Cl)(=[O:34])=[O:33])=[CH:28][CH:27]=1>N1C=CC=CC=1>[CH3:24][N:23]1[C:19]([C:17]([NH:16][C:11]2[CH:10]=[C:9]([O:8][C:5]3[CH:6]=[N:7][C:2]([NH:1][S:32]([C:29]4[CH:30]=[CH:31][C:26]([CH3:36])=[CH:27][CH:28]=4)(=[O:34])=[O:33])=[CH:3][CH:4]=3)[CH:14]=[C:13]([CH3:15])[CH:12]=2)=[O:18])=[CH:20][C:21]([CH3:25])=[N:22]1参加物
4
反応物 2
生成物 1
試薬・触媒・溶媒 1
実験手順
In the same manner as in Reference Example 4 and using N-{3-[(6-aminopyridin-3-yl)oxy]-5-methylphenyl}-1,3-dimethyl-1H-pyrazole-5-carboxamide (4.02 g, 9.79 mmol), p-toluenesulfonyl chloride (2.29 g, 12.0 mmol) and pyridine (30 mL) as starting materials, the title compound (3.88 g, 81%) was obtained as a colorless oil.
出典と根拠
- ORDレコード
- ord-8605b913e922455a9eb86181594531ce
- 出典データセット
- uspto-grants-2012_11
- 特許番号
- US08304557B2
関連ノート
読み込み中…