Thionyl Chloride → 3-[Chloro(cyclopentyl)methyl]-2-methyl-5-phenylfuran

HRID 1877066ノート

反応式

HRID 1877066 の反応式
[CH:1]1([CH:6]([C:8]2[CH:12]=[C:11]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=3)[O:10][C:9]=2[CH3:19])O)[CH2:5][CH2:4][CH2:3][CH2:2]1.S(Cl)([Cl:22])=O>C1(C)C=CC=CC=1>[Cl:22][CH:6]([CH:1]1[CH2:5][CH2:4][CH2:3][CH2:2]1)[C:8]1[CH:12]=[C:11]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[O:10][C:9]=1[CH3:19]

参加物

4

反応物 2

HCID 24386Thionyl ChlorideHCID 68509772Cyclopentyl(2-methyl-5-phenylfuran-3-yl)methanol

生成物 1

HCID 685140893-[Chloro(cyclopentyl)methyl]-2-methyl-5-phenylfuran収率 100%

試薬・触媒・溶媒 1

HCID 1140Toluene溶媒

実験手順

To a solution of cyclopentyl(2-methyl-5-phenylfuran-3-yl)methanol (0.9 g) in toluene (20 mL) was added thionyl chloride (0.5 mL), and the mixture was stirred at room temperature overnight. The solvent was evaporated under reduced pressure to give the title compound (1.0 g, 100%) as an oil.

後処理

  1. customThe solvent was evaporated under reduced pressure

出典と根拠

ORDレコード
ord-33ed6ed5150244c3820f26b7b43f1c9b
出典データセット
uspto-grants-2012_11
特許番号
US08309580B2

反応ノート

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